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IL28RA Antibody

CAT: 0223-30-351Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-30-351Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IL28RA belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB) . The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29) . The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B.The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB) . The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29) . The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
NCBI Gene ID
163702
Swiss Prot
Q8IU57
Accession Number
NP_734464
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IL28RA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store IL28RA antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
58 kDa, 54 kDa, 28 kDa
Applications Notes
IL28RA antibody can be used for detection of IL28RA by ELISA at 1:312500. IL28RA antibody can be used for detection of IL28RA by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
IFNLR1
NCBI Official Name
Interferon, lambda receptor 1
NCBI Organism
Homo sapiens
Background Reference 01
Dumoutier, L., (2004) J. Biol. Chem. 279 (31), 32269-32274.
Other Product Names
IL28RA, CRF2/12, IFNLR, IFNLR1, LICR2, il-28r1, IL28RA, IL-28R1
Tested Applications
ELISA, WB
Protein ID
25014103
Physical Properties
Liquid

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