IL2RG Antibody

• Background:

  IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.

• NCBI Gene ID:

  3561

• Swiss Prot:

  P31785

• Accession Number:

  P31785

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This IL2RG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-101 amino acids from the N-terminal region of human IL2RG.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Immunology, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  42 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  IL2RG

• NCBI Official Name:

  Cytokine receptor common subunit gamma

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ross, J.A., et al. J. Biol. Chem. 285 (6) :3582-3591 (2010)

• Background Reference 02:

  Ameratunga, R., et al. N. Z. Med. J. 122 (1304) :46-53 (2009)

• Background Reference 03:

  Clark, P.A., et al. Hum. Genet. 96 (4) :427-432 (1995)

• Other Product Names:

  Cytokine receptor common subunit gamma, Interleukin-2 receptor subunit gamma, IL-2 receptor subunit gamma, IL-2R subunit gamma, IL-2RG, gammaC, p64, CD132, IL2RG

• Tested Applications:

  WB, IF, Flow

• Protein ID:

  400048

• Physical Properties:

  Liquid