HIP2 Antibody

• Background:

  HIP2 belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.

• NCBI Gene ID:

  3093

• Swiss Prot:

  P61086

• Accession Number:

  NP_005330

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog, Zebrafish

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HIP2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HIP2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  22 kDa

• Applications Notes:

  HIP2 antibody can be used for detection of HIP2 by ELISA at 1:312500. HIP2 antibody can be used for detection of HIP2 by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  UBE2K

• NCBI Official Name:

  Ubiquitin-conjugating enzyme E2K

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lee, S.J., (2001) FEBS Lett. 503 (1), 61-64.

• Other Product Names:

  HIP2, HYPG, LIG, UBE2K, HIP2, UBC1, E2-25K

• Tested Applications:

  ELISA, WB

• Protein ID:

  4885417

• Physical Properties:

  Liquid