Products for Research Use Only
RegisterLogin

CLEC4M Antibody

CAT: 0223-29-747Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-29-747Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
CLEC4M is a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells. This gene is mapped to 19p13.3, in a cluster with the CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
NCBI Gene ID
10332
Swiss Prot
Q9H2X3
Accession Number
NP_055072
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLEC4M.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CLEC4M antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
44 kDa, 45 kDa, 43 kDa, 30 kDa, 30 kDa, 28 kDa
Applications Notes
CLEC4M antibody can be used for detection of CLEC4M by ELISA at 1:312500. CLEC4M antibody can be used for detection of CLEC4M by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CLEC4M
NCBI Official Name
C-type lectin domain family 4, member M
NCBI Organism
Homo sapiens
Background Reference 01
Liu, H., (2006) J. Infect. Dis. 193 (5), 698-702.
Other Product Names
CLEC4M, CD209L, CD299, DC-SIGN2, DC-SIGNR, DCSIGNR, HP10347, L-SIGN, LSIGN, MGC129964, MGC47866
Tested Applications
ELISA, WB, IHC
Protein ID
42542390
Physical Properties
Liquid

Related Products

CatalogName
55-762CLEC4F Antibody
42-155CLEC4C Antibody
33-011CLEC4E Antibody
13-690CLEC4G Antibody
59-256CLEC4D Antibody
18-780CLEC4A Antibody
61-654CLEC2B Antibody
55-503CLEC2L Antibody
59-378CLEC9A Antibody
26-760CLECL1 Antibody

Alternative Products

CatalogName
GWB-MP258FCLEC4M Antibody

Popular Products