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MUC1 Antibody

CAT: 0223-29-576Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-29-576Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MUC1 is a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.
NCBI Gene ID
4582
Swiss Prot
Q7Z552
Accession Number
NP_001037855
Host
Rabbit
Reactivity
Human, Mouse, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MUC1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MUC1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
22 kDa, 28 kDa, 28 kDa, 16 kDa, 17 kDa, 30 kDa
Applications Notes
MUC1 antibody can be used for detection of MUC1 by ELISA at 1:312500. MUC1 antibody can be used for detection of MUC1 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
MUC1
NCBI Official Name
Mucin 1, cell surface associated
NCBI Organism
Homo sapiens
Other Product Names
MUC1, CD227, EMA, PEM, PUM, mucin, MCD, KL-6, MAM6, MCKD, PEMT, H23AG, MCKD1, MUC-1, ADMCKD, ADMCKD1, CA 15-3, MUC-1/X, MUC1/ZD, MUC-1/SEC
Tested Applications
ELISA, WB, IHC
Protein ID
113206024
Physical Properties
Liquid

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