JMJD3 Antibody

CAT: 0223-29-186Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-29-186Size:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
JMJD3 is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
NCBI Gene ID
23135
Swiss Prot
O15054
Accession Number
AAH09994
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human JMJD3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store JMJD3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
70 kDa
Applications Notes
JMJD3 antibody can be used for detection of JMJD3 by ELISA at 1:1562500. JMJD3 antibody can be used for detection of JMJD3 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
KDM6B
NCBI Official Name
Lysine (K) -specific demethylase 6B
NCBI Organism
Homo sapiens
Other Product Names
JMJD3, KIAA0346, JMJD3
Tested Applications
ELISA, WB
Protein ID
14603031
Physical Properties
Liquid

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