ELF4 Antibody

• Background:

  ELF4 contains 1 ETS DNA-binding domain and belongs to the ETS family. It is transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. It transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. It acts synergistically with RUNX1 to transactivate the IL3 promoter and also transactivates the PRF1 promoter in natural killer (NK) cells. ELF4 plays a role in the development and function of NK and NK T-cells and in innate immunity.

• NCBI Gene ID:

  2000

• Swiss Prot:

  Q99607

• Accession Number:

  NP_001412

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ELF4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Tranfected 293T Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ELF4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  71 kDa

• Applications Notes:

  ELF4 antibody can be used for detection of ELF4 by ELISA at 1:312500. ELF4 antibody can be used for detection of ELF4 by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  ELF4

• NCBI Official Name:

  E74-like factor 4 (ets domain transcription factor)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Cho, J.Y., (2004) J. Biol. Chem. 279 (19), 19512-19522.

• Other Product Names:

  ELF4, MEF, ELFR

• Tested Applications:

  ELISA, WB

• Protein ID:

  4503555

• Physical Properties:

  Liquid