DDX6 Antibody

• Background:

  DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX6 encodes a DEAD box protein. It may contribute to the cell proliferation and carcinogenesis.

• NCBI Gene ID:

  1656

• Swiss Prot:

  P26196

• Accession Number:

  NP_004388

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DDX6.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store DDX6 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  52 kDa

• Applications Notes:

  DDX6 antibody can be used for detection of DDX6 by ELISA at 1:312500. DDX6 antibody can be used for detection of DDX6 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  DDX6

• NCBI Official Name:

  DEAD (Asp-Glu-Ala-Asp) box helicase 6

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Miyaji, K., et al., (2003) J. Viral Hepat. 10 (4), 241-248.

• Other Product Names:

  DDX6, P54, RCK, HLR2

• Tested Applications:

  ELISA, WB

• Protein ID:

  164664518

• Physical Properties:

  Liquid