Products for Research Use Only
RegisterLogin

KCNN3 Antibody

CAT: 0223-28-241Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-28-241Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein that is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits.
NCBI Gene ID
3782
Swiss Prot
Q9UGI6
Accession Number
NP_002240
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNN3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1224 - Daudi Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store KCNN3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
81 kDa, 48 kDa
Applications Notes
KCNN3 antibody can be used for detection of KCNN3 by ELISA at 1:62500. KCNN3 antibody can be used for detection of KCNN3 by western blot at 2 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
KCNN3
NCBI Official Name
Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
NCBI Organism
Homo sapiens
Background Reference 01
Kolski-Andreaco, A., et al., (2004) J. Biol. Chem. 279 (8), 6893-6904.
Other Product Names
KCNN3, SK3, hSK3, SKCA3, KCa2.3
Tested Applications
ELISA, WB
Protein ID
116805330
Physical Properties
Liquid

Related Products

CatalogName
42-935KCNC3 Antibody
42-239KCNN2 Antibody
42-090KCNQ3 Antibody
18-422KCNN4 Antibody
15-701KCNK3 Antibody
28-240KCNN1 Antibody
23-270KCNS3 Antibody
22-561KCND3 Antibody
28-238KCNK3 Antibody
57-914KCNQ3 Antibody

Alternative Products

CatalogName
DF13233-01KCNN3 Antibody
MBS9126368-01KCNN3 Polyclonal Antibody
MBS8245545-01Anti-KCNN3 Antibody
566280-01KCNN3

Popular Products