FOXK2 Antibody

• Background:

  FOXK2 contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements. Three alternatively spliced transcript variants encoding distinct isoforms have been described.The protein encoded by this gene contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements. Three alternatively spliced transcript variants encoding distinct isoforms have been described.

• NCBI Gene ID:

  3607

• Swiss Prot:

  Q01167

• Accession Number:

  NP_004505

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FOXK2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store FOXK2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  69 kDa, 50 kDa, 57 kDa

• Applications Notes:

  FOXK2 antibody can be used for detection of FOXK2 by ELISA at 1:12500. FOXK2 antibody can be used for detection of FOXK2 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  FOXK2

• NCBI Official Name:

  Forkhead box K2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Liu, P.P., et al., (2002) Proteins 49 (4), 543-553.

• Other Product Names:

  FOXK2, ILF, ILF1, ILF-1

• Tested Applications:

  ELISA, WB

• Protein ID:

  31563338

• Physical Properties:

  Liquid