TRIM3 Antibody

CAT: 0223-28-166Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-28-166Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by TRIM3 is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport.
NCBI Gene ID
10612
Swiss Prot
Q6ZTE7
Accession Number
NP_006449
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRIM3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer, Neuroscience
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TRIM3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
81 kDa
Applications Notes
TRIM3 antibody can be used for detection of TRIM3 by ELISA at 1:1562500. TRIM3 antibody can be used for detection of TRIM3 by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TRIM3
NCBI Official Name
Tripartite motif containing 3
NCBI Organism
Homo sapiens
Background Reference 01
Reymond, A., et al., (2001) EMBO J. 20 (9), 2140-2151.
Other Product Names
TRIM3, BERP, HAC1, RNF22, RNF97
Tested Applications
ELISA, WB, IHC
Protein ID
32454739
Physical Properties
Liquid

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