IRF4 Antibody

CAT: 0223-27-665Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-27-665Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IFN regulatory factor (IRF) -4 is a lymphoid/myeloid-restricted member of the IRF transcription factor family that plays an essential role in the homeostasis and function of mature lymphocytes. IRF-4 expression is tightly regulated in resting primary T cells and is transiently induced at the mRNA and protein levels after activation by Ag-mimetic stimuli such as TCR cross-linking or treatment with phorbol ester and calcium ionophore (PMA/ionomycin) .
NCBI Gene ID
3662
Swiss Prot
Q15306
Accession Number
NP_002451
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IRF4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Signal Transduction, Immunology
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store IRF4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
52 kDa
Applications Notes
IRF4 antibody can be used for detection of IRF4 by ELISA at 1:312500. IRF4 antibody can be used for detection of IRF4 by western blot at 5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
IRF4
NCBI Official Name
Interferon regulatory factor 4
NCBI Organism
Homo sapiens
Background Reference 01
Lehtonen, A., et al., (2005) J. Immunol. 175 (10), 6570-6579.
Other Product Names
IRF4, MUM1, LSIRF, NF-EM5
Tested Applications
ELISA, WB
Protein ID
167555104
Physical Properties
Liquid

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