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SIRT3 Antibody

CAT: 0223-27-579Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-27-579Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The SIRT3 gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT3 encodes a protein that is included in class I of the sirtuin family.
NCBI Gene ID
23410
Swiss Prot
Q9NTG7
Accession Number
NP_001017524
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SIRT3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SIRT3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
28 kDa, 44 kDa
Applications Notes
SIRT3 antibody can be used for detection of SIRT3 by ELISA at 1:62500. SIRT3 antibody can be used for detection of SIRT3 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SIRT3
NCBI Official Name
Sirtuin 3
NCBI Organism
Homo sapiens
Background Reference 01
Onyango, P., et al., (2002) Proc. Natl. Acad. Sci. U.S.A. 15 99 (21), 13653-8.
Other Product Names
SIRT3, SIR2L3
Tested Applications
ELISA, WB, IHC
Protein ID
63054862
Physical Properties
Liquid

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