RegisterLogin

ELF3 Antibody

CAT: 0223-27-528Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-27-528Size:100 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
ELF3 is a novel, highly tissue-restricted member of the ets transcription factor/oncogene family. ELF3 contains two putative DNA binding domains: an ETS domain, which is unique in that the 5' half shows relatively weak homology to known ets factors, and an A/T hook domain, found in HMG proteins and various other nuclear factors. In contrast to any known ets factors, ELF3 is expressed exclusively in epithelial cells. ELF3 is expected to be a critical regulator of epithelial cell differentiation. ETS factor ELF3 is a transcriptional regulator of angiopoietin-1 gene regulation in the setting of inflammation. ELF3 overexpressed early during human breast tumorigenesis. ELF3 expression confers a transformed and in vitro metastatic phenotype to otherwise normal MCF-12A cells. ELF3 mediates the expression of TGF-beta RII, and the transcriptional inhibition of ets-related transcription factor could be a one of the mechanisms of colonic carcinogenesis. ELF3 is positively and negatively modulated by other interacting proteins including Ku70, Ku86, p300, and CBP.
NCBI Gene ID
1999
Swiss Prot
P78545
Accession Number
NP_004424
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ELF3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. XBL-10426 - Fetal Thymus Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ELF3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
41 kDa
Applications Notes
ELF3 antibody can be used for detection of ELF3 by ELISA at 1:312500. ELF3 antibody can be used for detection of ELF3 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ELF3
NCBI Official Name
E74-like factor 3 (ets domain transcription factor, epithelial-specific)
NCBI Organism
Homo sapiens
Background Reference 01
Wang, H., (2004) J. Biol. Chem. 279 (24), 25241-25250.
Other Product Names
ELF3, ERT, ESX, EPR-1, ESE-1
Tested Applications
ELISA, WB
Protein ID
167235023
Physical Properties
Liquid

Related Products

CatalogName
45-527PELF3 Peptide
27-380ELF2 Antibody
56-629ELF4 Antibody
22-761ELF5 Antibody
22-978ELF2 Antibody
28-772ELF4 Antibody
45-526ELF1 Antibody
27-529ELF4 Antibody
62-712ELF4 Antibody
45-528ELF5 Antibody

Alternative Products

CatalogName
200188ELF3 Antibody
MBS9126393-01ELF3 Polyclonal Antibody
STJ115450Anti-ELF3 antibody
C38856ELF3 Conjugated Antibody
MBS8535901-01ELF3

Popular Products