CEBPB Antibody

CAT: 0223-27-319Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-27-319Size:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this intronless gene, CEBPB, is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
NCBI Gene ID
1051
Swiss Prot
P17676
Accession Number
NP_005185
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CEBPB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer, Signal Transduction, Immunology
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CEBPB antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
36 kDa
Applications Notes
CEBPB antibody can be used for detection of CEBPB by ELISA at 1:1562500. CEBPB antibody can be used for detection of CEBPB by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CEBPB
NCBI Official Name
CCAAT/enhancer binding protein (C/EBP), beta
NCBI Organism
Homo sapiens
Background Reference 01
Chen, C., et al., (2004) J. Biol. Chem. 279 (27), 27948-27956.
Other Product Names
CEBPB, LAP, LIP, CRP2, TCF5, IL6DBP, NF-IL6, C/EBP-beta
Tested Applications
ELISA, WB
Protein ID
28872796
Physical Properties
Liquid

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