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TRIM22 Antibody

CAT: 0223-27-251Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-27-251Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TRIM22 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. It localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
NCBI Gene ID
10346
Swiss Prot
Q8IYM9
Accession Number
NP_006065
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRIM22.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TRIM22 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
57 kDa
Applications Notes
TRIM22 antibody can be used for detection of TRIM22 by ELISA at 1:312500. TRIM22 antibody can be used for detection of TRIM22 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TRIM22
NCBI Official Name
Tripartite motif containing 22
NCBI Organism
Homo sapiens
Background Reference 01
Obad, S., (2007) J. Interferon Cytokine Res. 27 (10), 857-864.
Other Product Names
TRIM22, GPSTAF50, RNF94, STAF50
Tested Applications
ELISA, WB
Protein ID
117938316
Physical Properties
Liquid

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