COG2 Antibody

• Background :

  Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG2. Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG2 (Ungar et al., 2002 [PubMed 11980916]) .

• NCBI Gene ID :

  22796

• Swiss Prot :

  Q14746

• Accession Number :

  NP_031383

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COG2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Antibody is purified by peptide affinity chromatography method.

• Positive Control :

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store COG2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  83 kDa

• Applications Notes :

  COG2 antibody can be used for detection of COG2 by ELISA at 1:62500. COG2 antibody can be used for detection of COG2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  COG2

• NCBI Official Name :

  Component of oligomeric golgi complex 2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Sohda, M., (2007) Traffic 8 (3), 270-284.

• Other Product Names :

  COG2, LDLC

• Tested Applications :

  ELISA, WB

• Protein ID :

  6678676

• Physical Properties :

  Liquid