COG8 Antibody

• Background:

  This gene encodes a protein that is a component of the conserved oligomeric Golgi (COG) complex, a multiprotein complex that plays a structural role in the Golgi apparatus, and is involved in intracellular membrane trafficking and glycoprotein modification. Mutations in this gene cause congenital disorder of glycosylation, type IIh, a disease that is characterized by under-glycosylated serum proteins, and whose symptoms include severe psychomotor retardation, failure to thrive, seizures, and dairy and wheat product intolerance.

• NCBI Gene ID:

  84342

• Swiss Prot:

  Q96MW5

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 394-612 of human COG8 (NP_115758.3) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Jurkat

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 68kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  COG8

• Positive Control 2:

  A-431

• NCBI Official Name:

  Component of oligomeric golgi complex 8

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Dependent on RIC1, conserved oligomeric golgi complex component 8, FLJ22315, DOR1, component of oligomeric golgi complex 8, COG8, CDG2H

• Tested Applications:

  WB

• Physical Properties:

  Liquid