COX3 Antibody

• Background :

  COX3 is a multi-pass membrane protein. It belongs to the cytochrome c oxidase subunit 3 family. Defects in COX3 are a cause of Leber hereditary optic neuropathy (LHON) and cytochrome c oxidase deficiency (COX deficiency) . Defects in MT-CO3 are also found in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome and recurrent myoglobinuria.

• NCBI Gene ID :

  4514

• Swiss Prot :

  P00414

• Accession Number :

  NP_536849

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COX3.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Membrane

• Purification :

  Antibody is purified by peptide affinity chromatography method.

• Positive Control :

  721_B Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store COX3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  29 kDa

• Applications Notes :

  COX3 antibody can be used for detection of COX3 by ELISA at 1:1562500. COX3 antibody can be used for detection of COX3 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  COX3

• NCBI Official Name :

  Mitochondrially encoded cytochrome c oxidase III

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  COX3, MTCO3, COIII, COX3

• Tested Applications :

  ELISA, WB

• Protein ID :

  17981859

• Physical Properties :

  Liquid