Cox2 Antibody

• Background:

  Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.

• NCBI Gene ID:

  5743

• Swiss Prot:

  P35354

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 375-604 of human Cox2 (NP_000954.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  A-549

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 80kDa

• Fragment:

  IgG

• Symbol:

  PTGS2

• Positive Control 2:

  HeLa

• Positive Control 3:

  Mouse spleen

• Positive Control 4:

  Mouse lung

• Positive Control 5:

  Rat lung

• Positive Control 6:

  Rat kidney

• NCBI Official Name:

  Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  COX-2, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), COX2, COX-2, PHS-2, PGG/HS, PGHS-2, hCox-2, prostaglandin G/H synthase and cyclooxygenase

• Tested Applications:

  WB, IHC, IF, IP

• Physical Properties:

  Liquid