SLC27A2 Antibody

SLC27A2 is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy.The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy.

11001

O14975

NP_003636

Human, Mouse, Rat

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC27A2.

Unconjugated

Primary Antibodies

Membrane, Signal Transduction

Antibody is purified by peptide affinity chromatography method.

Cat. No. 1201 - HeLa Cell Lysate

Batch dependent

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

None

Blue Ice

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SLC27A2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

70 kDa

SLC27A2 antibody can be used for detection of SLC27A2 by ELISA at 1:62500. SLC27A2 antibody can be used for detection of SLC27A2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

SLC27A2

Solute carrier family 27 (fatty acid transporter), member 2

Homo sapiens

Mihalik, S.J., (2002) J. Biol. Chem. 277 (27), 24771-24779.

SLC27A2, ACSVL1, FACVL1, FATP2, HsT17226, VLACS, VLCS, hFACVL1

ELISA, WB

227499619