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HTR3C Antibody

CAT: 0223-25-257Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-25-257Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HTR3C is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3.
NCBI Gene ID
170572
Swiss Prot
Q8WXA8
Accession Number
NP_570126
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HTR3C.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HTR3C antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
50 kDa
Applications Notes
HTR3C antibody can be used for detection of HTR3C by ELISA at 1:62500. HTR3C antibody can be used for detection of HTR3C by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
HTR3C
NCBI Official Name
5-hydroxytryptamine (serotonin) receptor 3C, ionotropic
NCBI Organism
Homo sapiens
Background Reference 01
Fasching, P.A., (er) J. Cancer Res. Clin. Oncol. (2008) In press.
Other Product Names
HTR3C
Tested Applications
ELISA, WB
Protein ID
47519867
Physical Properties
Liquid

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