IL-10 Antibody [9D7], Rabbit IgG

• Other Statements:

  This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.

• NCBI Gene ID:

  3586

• Swiss Prot:

  P22301

• Reactivity:

  Human

• Immunogen:

  Rats are immunised with synthetic oligopeptide (containing an N-terminal cysteine) -carrier protein conjugates. IL-10 was conjugated to JES3. The mouse non-secreting myeloma fusion partner P3X63-AG8.653, is fused to immunised rat splenocytes to produce heterohybridomas secreting rat antibody. Bioassays were used to identify neutralising mAbs, and immunochemical screens were used to identify mAbs that bind the cytokine.

• Clonality:

  Recombinant Monoclonal

• Clone:

  9D7

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Chemokines & Cytokines

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% Proclin 300.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

• Fragment:

  IgG kappa

• Symbol:

  IL10

• NCBI Official Name:

  HGNC:HGNC:5962

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Human cytokine synthesis inhibitory factor, GVHDS, IL10, Interleukin 10, Interleukin-10, IL10A, TGIF, JES3-9D7, JES3 9D7

• Tested Applications:

  Neutralization Assay, ELISA, IHC, IF, IP, Crystallography

• Species:

  Rabbit