CHCHD3 Antibody

• Background:

  The protein encoded by this gene is an inner mitochondrial membrane scaffold protein. Absence of the encoded protein affects the structural integrity of mitochondrial cristae and leads to reductions in ATP production, cell growth, and oxygen consumption. This protein is part of the mitochondrial contact site and cristae organizing system (MICOS) . Several transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  54927

• Swiss Prot:

  Q9NX63

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-227 of human CHCHD3 (NP_060282.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  A-549

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 30kDa

• Fragment:

  IgG

• Symbol:

  CHCHD3

• Positive Control 2:

  HeLa

• Positive Control 3:

  A-431

• Positive Control 4:

  Jurkat

• Positive Control 5:

  HepG2

• Positive Control 6:

  Mouse kidney

• NCBI Official Name:

  Coiled-coil-helix-coiled-coil-helix domain containing 3

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CHCHD3, FLJ20420, coiled-coil-helix-coiled-coil-helix domain containing 3, MINOS3

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid