IRS2 Antibody

• Background:

  This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.

• NCBI Gene ID:

  8660

• Swiss Prot:

  Q9Y4H2

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 510-650 of human IRS2 (NP_003740.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Growth Factors, Immunology, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  LO2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 170kDa

• Fragment:

  IgG

• Symbol:

  IRS2

• Positive Control 2:

  Mouse brain

• Positive Control 3:

  Mouse liver

• Positive Control 4:

  Rat liver

• NCBI Official Name:

  Insulin receptor substrate 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Insulin receptor substrate 2, IRS-2, IRS2

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid