ETFA Antibody

• Background :

  ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID :

  2108

• Swiss Prot :

  P13804

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-333 of human ETFA (NP_000117.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  MCF7

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 35kDa

• Fragment :

  IgG

• Symbol :

  ETFA

• Positive Control 2 :

  A-549

• Positive Control 3 :

  SW620

• Positive Control 4 :

  HepG2

• Positive Control 5 :

  Mouse liver

• Positive Control 6 :

  Mouse kidney

• NCBI Official Name :

  Electron-transfer-flavoprotein, alpha polypeptide

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  ETFA, EMA, GA2, MADD

• Tested Applications :

  WB, IHC, IF

• Physical Properties :

  Liquid