SUMO4 Antibody

• Background :

  This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism.

• NCBI Gene ID :

  387082

• Swiss Prot :

  Q6EEV6

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human SUMO4 (NP_001002255.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Immunology, Transcription

• Purification :

  Affinity purification

• Positive Control :

  HepG2

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 15kDa

• Fragment :

  IgG

• Symbol :

  SUMO4

• Positive Control 2 :

  MCF7

• Positive Control 3 :

  Mouse kidney

• Positive Control 4 :

  Mouse spleen

• Positive Control 5 :

  Rat spleen

• NCBI Official Name :

  Small ubiquitin-related modifier 4

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  Small ubiquitin-related modifier 4, SUMO-4, Small ubiquitin-like protein 4, SUMO4, SMT3H4

• Tested Applications :

  WB, IF

• Physical Properties :

  Liquid