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ACTR1A Antibody

CAT: 0223-22-277Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-22-277Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.
NCBI Gene ID
10121
Swiss Prot
P61163
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 187-376 of human ACTR1A (NP_005727.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 43kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
ACTR1A
Positive Control 2
Mouse skeletal muscle
Positive Control 3
Mouse spleen
Positive Control 4
Mouse lung
Positive Control 5
Rat brain
NCBI Official Name
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
NCBI Organism
Homo sapiens
Other Product Names
ACTR1A, ARP1, CTRN1
Tested Applications
WB
Physical Properties
Liquid

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