HAT1 Antibody

• Background:

  The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.

• NCBI Gene ID:

  8520

• Swiss Prot:

  O14929

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 245-419 of human HAT1 (NP_003633.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  MCF7

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 50kDa

• Fragment:

  IgG

• Symbol:

  HAT1

• Positive Control 2:

  SW480

• Positive Control 3:

  Jurkat

• Positive Control 4:

  293T

• Positive Control 5:

  HeLa

• Positive Control 6:

  HepG2

• NCBI Official Name:

  Histone acetyltransferase type B catalytic subunit

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase 1, HAT1, KAT1

• Tested Applications:

  WB, IHC, IF, ChIP

• Physical Properties:

  Liquid