GARS Antibody

• Background :

  This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha) 2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID :

  2617

• Swiss Prot :

  P41250

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 60-370 of human GARS (NP_002038.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Affinity purification

• Positive Control :

  Jurkat

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 83kDa

• Fragment :

  IgG

• Symbol :

  GARS

• Positive Control 2 :

  293T

• Positive Control 3 :

  U-87MG

• Positive Control 4 :

  Raji

• Positive Control 5 :

  M21

• Positive Control 6 :

  HT-29

• NCBI Official Name :

  Glycyl-tRNA synthetase

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  CMT2D, DSMAV, GlyRS, HMN5, SMAD1, glycine--tRNA ligase, AP-4-A synthetase, Charcot-Marie-Tooth neuropathy 2D, Charcot-Marie-Tooth neuropathy, neuronal type, D, ap4A synthetase, diadenosine tetraphosphate synthetase

• Tested Applications :

  WB, IHC, IF

• Physical Properties :

  Liquid