CPT1A Antibody

• Background:

  The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  1374

• Swiss Prot:

  P50416

• Host:

  Rabbit

• Reactivity:

  Human, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 497-756 of human CPT1A (NP_001027017.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  22Rv1

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 90kDa

• Fragment:

  IgG

• Symbol:

  CPT1A

• NCBI Official Name:

  Carnitine palmitoyltransferase 1A (liver)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CPT1A, CPT1, CPT1-L, L-CPT1

• Tested Applications:

  WB, IF, IP

• Physical Properties:

  Liquid