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CD9 Antibody

CAT: 0223-8531-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-8531-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD9 Antibody: CD9 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Like other tetraspanins, CD9 is a cell surface glycoproteins play a role in many cellular processes including differentiation, adhesion, and signal transduction (1) . CD9 expression plays a critical role in the suppression of cancer cell motility and metastasis. In one study, the knockdown of CD9 expression suppressed the metastatic capacity of human breast cancer cells (2), while other results have shown the opposite effect, suggesting that different proteins associated with CD9 account for its abilities to promote or suppress metastasis (3) .
NCBI Gene ID
928
Swiss Prot
P21926
Accession Number
NP_001760
Host
Rabbit
Reactivity
Human
Immunogen
CD9 antibody was raised against a peptide corresponding to 19 amino acids near the center of human CD9.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
CD9 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1384 - Human Uterus Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Cat: (90%), Bovine: (89%), Mouse: (84%), Rat: (84%), Boar: (78%)
Buffer
CD9 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
CD9 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Symbol
CD9
NCBI Official Name
CD9
NCBI Organism
Homo sapiens
Background Reference 01
Murayama Y, Oritani K, and Tsutsui S. Novel CD9-targeted therapies in gastric cancer. World J. Gastroenterol. 2015; 21:3206-13.
Background Reference 02
Rappa G, Green TM, Karbanova J, Corbeil D, et al. Tetraspanin CD9 determines invasiveness and tumorigenicity of human breast cancer cells. Oncotarget 2015; 6:7970-91.
Background Reference 03
Zoller M. Tetraspanins: push and pull in suppressing and promoting metastasis. Nat. Rev. Cancer 2009; 9:40-55.
Other Product Names
CD9 Antibody: CD9 molecule, MIC3, MRP-1, BTCC-1, DRAP-27, TSPAN29, TSPAN-29
Tested Applications
ELISA, WB
Protein ID
4502693
Physical Properties
Liquid

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