RAB8B Antibody

• Background:

  RAB proteins, like RAB8B, are low molecular mass monomeric GTPases that localize on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB proteins function in intracellular vesicle transport by aiding in the docking and/or fusion of vesicles with their target membranes (summary by Chen et al., 1997 [PubMed 9030196]) .

• NCBI Gene ID:

  51762

• Swiss Prot:

  Q92930

• Accession Number:

  Q92930

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This RAB8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-198 amino acids from the C-terminal region of human RAB8B.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  24 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  RAB8B

• NCBI Official Name:

  Ras-related protein Rab-8B

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Heidrych, P., et al. Hum. Mol. Genet. 17 (23) :3814-3821 (2008)

• Background Reference 02:

  Wu, C., et al. Proteomics 7 (11) :1775-1785 (2007)

• Background Reference 03:

  Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

• Background Reference 04:

  Lau, A.S., et al. Endocrinology 144 (4) :1549-1563 (2003)

• Other Product Names:

  Ras-related protein Rab-8B, RAB8B

• Tested Applications:

  WB

• Protein ID:

  13638434

• Physical Properties:

  Liquid