ENPP2 Antibody

• Background:

  The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.

• NCBI Gene ID:

  5168

• Swiss Prot:

  Q13822

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 564-863 of human ENPP2 (NP_001035181.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HepG2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 110-115kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  ENPP2

• Positive Control 2:

  A-549

• Positive Control 3:

  Mouse kidney

• NCBI Official Name:

  Ectonucleotide pyrophosphatase/phosphodiesterase 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ENPP2, ectonucleotide pyrophosphatase/phosphodiesterase 2, ATX, ATX-X, AUTOTAXIN, LysoPLD, NPP2, PD-IALPHA, PDNP2, E-NPP 2, autotaxin-t, ectonucleotide pyrophosphatase/phosphodiesterase family member 2, extracellular lysophospholipase D, phosphodiesterase

• Tested Applications:

  WB

• Physical Properties:

  Liquid