ACADM Antibody

• Background:

  This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  34

• Swiss Prot:

  P11310

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ACADM (NP_000007.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HT-29

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 46kDa

• Fragment:

  IgG

• Symbol:

  ACADM

• Positive Control 2:

  HepG2

• Positive Control 3:

  U-251MG

• Positive Control 4:

  K-562

• Positive Control 5:

  Mouse liver

• Positive Control 6:

  Mouse kidney

• NCBI Official Name:

  Acyl-CoA dehydrogenase, C-4 to C-12 straight chain

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ACADM, ACAD1, MCAD, MCADH

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid