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PSMB9 Antibody

CAT: 0223-18-060Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-18-060Size:100 µL
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Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex) . Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit.
NCBI Gene ID
5698
Swiss Prot
P28065
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-219 of human PSMB9 (NP_002791.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
THP-1
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 22kDa
Fragment
IgG
Symbol
PSMB9
Positive Control 2
DU145
Positive Control 3
Mouse liver
NCBI Official Name
Proteasome (prosome, macropain) subunit, beta type, 9
NCBI Organism
Homo sapiens
Other Product Names
PSMB9, RING12, PSMB6i, proteasome beta 9 subu, proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2), multicatalytic endopeptidase complex chain 7, MGC70470, macropain chain 7, low molecular mass protein 2, LMP2, beta1i
Tested Applications
WB, IF
Physical Properties
Liquid

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