PSMB2 Antibody

• Background:

  The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

• NCBI Gene ID:

  5690

• Swiss Prot:

  P49721

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human PSMB2 (NP_002785.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  22Rv1

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 23kDa

• Fragment:

  IgG

• Symbol:

  PSMB2

• Positive Control 2:

  U-937

• Positive Control 3:

  K-562

• Positive Control 4:

  U-87MG

• Positive Control 5:

  HT-29

• Positive Control 6:

  HeLa

• NCBI Official Name:

  Proteasome (prosome, macropain) subunit, beta type, 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PSMB2, HC7-I, MGC104215, MGC126885

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid