SUMF2 Antibody

• Background:

  The catalytic sites of sulfatases are only active if they contain a unique amino acid, C-alpha-formylglycine (FGly) . The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum. This protein has low levels of FGly-generating activity but can heterodimerize with another family member - a protein with high levels of FGly-generating activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

• NCBI Gene ID:

  25870

• Swiss Prot:

  Q8NBJ7

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 45-320 of human SUMF2 (NP_056226.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  U-87MG

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 34kDa

• Fragment:

  IgG

• Symbol:

  SUMF2

• Positive Control 2:

  A-549

• Positive Control 3:

  HepG2

• Positive Control 4:

  BxPC-3

• NCBI Official Name:

  Sulfatase modifying factor 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PFGE, inactive C-alpha-formylglycine-generating enzyme 2, C-alpha-formyglycine-generating enzyme 2, C-alpha-formylglycine-generating enzyme 2, epididymis secretory sperm binding protein, paralog of formylglycine-generating enzyme, paralog of the formylglycine-generating enzyme

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid