NFATC4 Antibody

• Background:

  This gene encodes a member of the nuclear factor of activated T cells (NFAT) protein family. The encoded protein is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase, calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of interleukin-2 and interleukin-4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

• NCBI Gene ID:

  4776

• Swiss Prot:

  Q14934

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 560-710 of human NFATC4 (NP_004545.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Signal Transduction, Transcription

• Purification:

  Affinity purification

• Positive Control:

  SKOV3

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 108kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  NFATC4

• Positive Control 2:

  HepG2

• Positive Control 3:

  A-549

• Positive Control 4:

  Mouse lung

• Positive Control 5:

  Mouse kidney

• Positive Control 6:

  Mouse brain

• NCBI Official Name:

  Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  NFATC4, NFAT3, NF-AT3, NF-ATC4

• Tested Applications:

  WB

• Physical Properties:

  Liquid