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ANGPT1 Antibody

CAT: 0223-15-838Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-15-838Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
NCBI Gene ID
284
Swiss Prot
Q15389
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 161-293 of human ANGPT1 (NP_001186788.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Growth Factors
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 54/57kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
ANGPT1
Positive Control 2
Mouse heart
Positive Control 3
Rat heart
NCBI Official Name
Angiopoietin 1
NCBI Organism
Homo sapiens
Other Product Names
ANGPT1, angiopoietin 1, ANG1, AGPT, AGP1, KIAA0003
Tested Applications
WB
Physical Properties
Liquid

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