GNAQ Antibody

• Background:

  This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.

• NCBI Gene ID:

  2776

• Swiss Prot:

  P50148

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-359 of human GNAQ (NP_002063.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cancer, Cell Cycle, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  DU145

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 42kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  GNAQ

• Positive Control 2:

  OVCAR3

• Positive Control 3:

  HT-29

• Positive Control 4:

  U-251MG

• Positive Control 5:

  LO2

• Positive Control 6:

  Mouse brain

• NCBI Official Name:

  Guanine nucleotide binding protein (G protein), q polypeptide

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  GAQ, G-ALPHA-q, guanine nucleotide binding protein (G protein), q polypeptide, GNAQ, GAQ

• Tested Applications:

  WB

• Physical Properties:

  Liquid