TRIM2 Antibody

• Background :

  The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID :

  23321

• Swiss Prot :

  Q9C040

• Host :

  Rabbit

• Reactivity :

  Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 100-300 of human TRIM2 (NP_056086.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle

• Purification :

  Affinity purification

• Positive Control :

  Mouse small intestine

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 81kDa

• Fragment :

  IgG

• Symbol :

  TRIM2

• NCBI Official Name :

  Tripartite motif containing 2

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  Tripartite motif-containing protein 2, tripartite motif protein TRIM2, tripartite motif protein 2, RING finger protein 86, RNF86, KIAA0517, tripartite motif-containing 2, TRIM2

• Tested Applications :

  WB, IHC

• Physical Properties :

  Liquid