TRIM2 Antibody

• Background:

  The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  23321

• Swiss Prot:

  Q9C040

• Host:

  Rabbit

• Reactivity:

  Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 100-300 of human TRIM2 (NP_056086.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  Mouse small intestine

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 81kDa

• Fragment:

  IgG

• Symbol:

  TRIM2

• NCBI Official Name:

  Tripartite motif containing 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Tripartite motif-containing protein 2, tripartite motif protein TRIM2, tripartite motif protein 2, RING finger protein 86, RNF86, KIAA0517, tripartite motif-containing 2, TRIM2

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid