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HRH1 Antibody

CAT: 0223-15-434Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-15-434Size:100 µL
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Background
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. It has been associated with multiple processes, including memory and learning, circadian rhythm, and thermoregulation. It is also known to contribute to the pathophysiology of allergic diseases such as atopic dermatitis, asthma, anaphylaxis and allergic rhinitis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
NCBI Gene ID
3269
Swiss Prot
P35367
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein of human HRH1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Growth Factors, Immunology, Innate Immunity, Signal Transduction
Purification
Affinity purification
Positive Control
Human colon
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 56kDa
Fragment
IgG
Symbol
HRH1
NCBI Official Name
Histamine receptor H1
NCBI Organism
Homo sapiens
Other Product Names
HRH1, histamine receptor H1, HGNC:5182, H1-R, hisH1, histamine receptor, subclass H1
Tested Applications
WB, IHC
Physical Properties
Liquid

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