PSMG2 Antibody

• Background:

  Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.

• NCBI Gene ID:

  56984

• Swiss Prot:

  Q969U7

• Accession Number:

  Q969U7

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PSMG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-246 amino acids from the C-terminal region of human PSMG2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  29 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PSMG2

• NCBI Official Name:

  Proteasome assembly chaperone 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Cooper, J.D., et al. Nat. Genet. 40 (12) :1399-1401 (2008)

• Background Reference 02:

  Barrett, J.C., et al. Nat. Genet. 40 (8) :955-962 (2008)

• Background Reference 03:

  Miyagawa, H., et al. Rheumatology (Oxford) 47 (2) :158-164 (2008)

• Background Reference 04:

  Parkes, M., et al. Nat. Genet. 39 (7) :830-832 (2007)

• Other Product Names:

  Proteasome assembly chaperone 2, PAC-2, Hepatocellular carcinoma-susceptibility protein 3, Tumor necrosis factor superfamily member 5-induced protein 1, PSMG2 {ECO:0000312|EMBL:AAH133561}

• Tested Applications:

  WB

• Protein ID:

  74731063

• Physical Properties:

  Liquid