USP7 Antibody

• Background:

  The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder.

• NCBI Gene ID:

  7874

• Swiss Prot:

  Q93009

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 206-1102 of human USP7 (NP_003461.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  MCF7

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 138kDa

• Fragment:

  IgG

• Symbol:

  USP7

• Positive Control 2:

  HeLa

• Positive Control 3:

  Rat testis

• NCBI Official Name:

  Ubiquitin specific peptidase 7 (herpes virus-associated)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  USP7, Deubiquitinating enzyme 7, HAUSP, TEF1, Ubiquitin specific protease 7, Ubiquitin thioesterase 7

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid