GARS Antibody

• Background:

  This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha) 2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  2617

• Swiss Prot:

  P41250

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 60-370 of human GARS (NP_002038.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  K-562

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 70-83kDa

• Fragment:

  IgG

• Symbol:

  GARS

• Positive Control 2:

  Mouse lung

• Positive Control 3:

  Mouse liver

• NCBI Official Name:

  Glycyl-tRNA synthetase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CMT2D, DSMAV, GlyRS, HMN5, SMAD1, glycine--tRNA ligase, AP-4-A synthetase, Charcot-Marie-Tooth neuropathy 2D, Charcot-Marie-Tooth neuropathy, neuronal type, D, ap4A synthetase, diadenosine tetraphosphate synthetase

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid