MYO6 Antibody

• Background:

  This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

• NCBI Gene ID:

  4646

• Swiss Prot:

  Q9UM54

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1016-1285 of human MYO6 (NP_004990.3) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HT-29

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 150kDa

• Fragment:

  IgG

• Symbol:

  MYO6

• Positive Control 2:

  Mouse brain

• Positive Control 3:

  Mouse kidney

• NCBI Official Name:

  Myosin VI

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  DFNA22, DFNB37, unconventional myosin-VI, unconventional myosin-6

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid