POLE2 Antibody

• Background:

  DNA polymerase epsilon, which is involved in DNA repair and replication, is composed of a large catalytic subunit and a small accessory subunit. The protein encoded by this gene represents the small subunit (B) . Defects in this gene have been linked to colorectal cancer and to combined immunodeficiency.

• NCBI Gene ID:

  5427

• Swiss Prot:

  P56282

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human POLE2 (NP_002683.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 59kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  POLE2

• Positive Control 2:

  Mouse heart

• NCBI Official Name:

  DNA polymerase epsilon 2, accessory subunit

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  DPE2, DNA polymerase epsilon subunit 2, DNA polymerase II subunit 2, DNA polymerase epsilon subunit B, polymerase (DNA directed), epsilon 2 (p59 subunit), polymerase (DNA directed), epsilon 2, accessory subunit, polymerase (DNA) epsilon 2, accessory subunit

• Tested Applications:

  WB

• Physical Properties:

  Liquid