GJA1 Antibody

• Background:

  This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations.

• NCBI Gene ID:

  2697

• Swiss Prot:

  P17302

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 233-382 of human GJA1 (NP_000156.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Immunology, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  SKOV3

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 38kDa

• Fragment:

  IgG

• Symbol:

  GJA1

• Positive Control 2:

  Mouse lung

• Positive Control 3:

  Mouse brain

• Positive Control 4:

  Rat brain

• NCBI Official Name:

  Gap junction protein, alpha 1, 43kDa

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  GJA1, HSS, CMDR, CX43, GJAL, ODDD, AVSD3, HLHS1, DFNB38

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid