NF-kB p65 Antibody

• Background:

  NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  5970

• Swiss Prot:

  Q04206

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human NF-kB p65 (NP_068810.3) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cancer, Cell Cycle, Immunology, Neuroscience, Obesity, Signal Transduction, Transcription

• Purification:

  Affinity purification

• Positive Control:

  NIH/3T3

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 65kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  RELA

• Positive Control 2:

  Jurkat

• Positive Control 3:

  BT-474

• Positive Control 4:

  Mouse lung

• Positive Control 5:

  Mouse liver

• Positive Control 6:

  Rat lung

• NCBI Official Name:

  V-rel avian reticuloendotheliosis viral oncogene homolog A

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  RELA, p65, NFKB3

• Tested Applications:

  WB

• Physical Properties:

  Liquid